Author: Marie-Luise Winz

After a (way too) long silence, I am proud to announce our first research paper is out as a preprint on BioRXiv! This is primarily Max' work, but with important contributions from Lena, too! Great collaboration also with Liz Petfalski in Edinburgh and Tamer Butto here at IPBS. We combine high-throughput UV-crosslinking + sequencing, nanopore sequencing, proteomics and low throughput Northern and Western blot analyses. With this, we show that the absence of yeast protein New1, a homolog of yeast translation elongation factor eEF3, leads to ribosomal collisions at specific C-terminal codons. This leads to degradation of particular mRNAs via no-go decay, affecting some of the most abundant mRNAs in yeast cells, and reducing the corresponding protein levels! We are very happy and proud to now be able to show this to the world! Check out the preprint here: https://www.biorxiv.org/content/10.1101/2024.11.26.625534v1

As time is passing on, our first M.Sc. and B.Sc. students have already finished. Thanks for joining us, Thea and Leonie! It was a pleasure hosting you.

In the meantime, Julia Melke has also started (and is about to finish) her B.Sc. thesis.

And we have students joining us over the summer, too, for internships. 🙂

More big news from the Winz lab: Thea and Leonie have started their M.Sc. and B.Sc. theses in our group! The lab is now really filling up 🙂 Good luck on our thesis work!

Thea, our first intern has already finished her interhsip a little while ago. We are happy to hear that she decided to join our team as an M.Sc. student next year :)! Looking forward to welcoming you again!

Last week, Kaushik has started his PhD thesis in our lab. Welcome Kaushik, we are really happy to finally have you here! As a perfect welcome, he got to join in our first CRAC experiment :D.

Success!!!  We are excited, elated, more than happy to let you know that the collaborative research centre (SFB) RMaP - RNA modification and processing that we are part of is being FUNDED!!! 🙂

This also means that we can recruit one more PhD student to the lab - see Jobs. Funding is available from 1st of July 2021, so please apply ASAP!

Here are also 2 press releases about our and other funded collaborative research centres.

https://www.uni-mainz.de/presse/aktuell/13717_DEU_HTML.php

https://www.dfg.de/service/presse/pressemitteilungen/2021/pressemitteilung_nr_16/index.html

A warm WELCOME to Lena and Max who have both arrived in the lab on 1st of March. 🙂 Looking forward to doing fantastic Science with you!

As more and more machines are arriving, we are getting closer to being a functioning lab. We are getting ready to receive a big box full of strains from my Edinburgh postdoc and getting more and more excited to soon be doing research again 🙂

Also, there's news on the recruitment side. We have been in conversation with a promising candidate interested in doing a PhD in Winz lab, and he has accepted our offer. Looking forward 😀 to working with him, starting February (?) 2021! We will post more information once this is official... Stay tuned!