After a (way too) long silence, I am proud to announce our first research paper is out as a preprint on BioRXiv! This is primarily Max' work, but with important contributions from Lena, too! Great collaboration also with Liz Petfalski in Edinburgh and Tamer Butto here at IPBS. We combine high-throughput UV-crosslinking + sequencing, nanopore sequencing, proteomics and low throughput Northern and Western blot analyses. With this, we show that the absence of yeast protein New1, a homolog of yeast translation elongation factor eEF3, leads to ribosomal collisions at specific C-terminal codons. This leads to degradation of particular mRNAs via no-go decay, affecting some of the most abundant mRNAs in yeast cells, and reducing the corresponding protein levels! We are very happy and proud to now be able to show this to the world! Check out the preprint here: https://www.biorxiv.org/content/10.1101/2024.11.26.625534v1